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Human CA125/MUC16 ELISA Kit
$350.00 – $450.00
| Sample Type | Serum, plasma, cell culture supernatant, and other biological samples |
|---|---|
| Sample Volume | 50 μL |
| Sensitivity | 0.41 pg/mL |
| Range | 15.63 pg/mL – 1000 pg/mL |
| Assay Time | 3.5 h |
| Recovery | 92% – 117% |
| Average Recovery | 1.05 |
| Intra Precision | 3.2% – 4.1% |
| Inter-Precision | 1.7%-2.7% |
| Platform | ELISA |
| Plate | Detachable 96-well plate |
| Size | 96T/48T |
| Storage | If the reagent kit is unopened, it should be stored at 4℃. However, if it has been opened, the standard solution should be stored at -20℃, while the other components should be stored at 4℃. |
| Delivery | 4℃ blue ice transportation |
| Components | 96-well polystyrene enzyme-linked immunosorbent assay (ELISA) plate coated with anti-CA125/MUC16 monoclonal antibody Human CA125/MUC16 freeze-dried standard Human CA125/MUC16 detect Antibody Standard Diluent Assay Buffer(10×) Substrate TMB Stop Solution Washing Buffer(20×) Sealing Film |
| Assay Principle | This kit utilizes the double antibody sandwich enzyme-linked immunosorbent assay (ELISA) detection technique.Specific anti-human CA125 antibodies are precoated on a high-affinity ELISA plate. Standard samples, test samples, and biotinylated detection antibodies are added to the wells of the ELISA plate. After incubation, CA125 present in the samples binds to the solid-phase antibodies and the detection antibodies. After washing to remove unbound substances, streptavidin-HRP labeled with horseradish peroxidase is added. After washing, a colorimetric substrate, TMB, is added and the plate is incubated in the dark for color development. The intensity of the color reaction is directly proportional to the concentration of CA125 in the samples.A stop solution is added to terminate the reaction, and the absorbance value is measured at a wavelength of 450 nm (with a reference wavelength range of 570-630 nm). |
Targets
MUC16
MUC16 Target Infomation Overview
- Target Symbol: MUC16, mucin 16, cell surface associated
- Gene Groups: Mucins
- Alias: CA125; FLJ14303; CA-125
- Alias Names: cancer antigen 125
MUC16, mucin 16, cell surface associated Target Infomation by Species
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Human MUC16 Target Information
- Target Symbol: MUC16, mucin 16, cell surface associated
- Alias:
- CA-125
- CA125
- CA125 ovarian cancer antigen
- cancer antigen 125
- FLJ14303
- MUC-16
- mucin 16
- mucin-16
- mucin-16 long isoform
- mucin-16 short isoform
- ovarian cancer-related tumor marker CA125
- ovarian carcinoma antigen CA125
- NCBI_Gene: 94025
- UniProtKB: Q8WXI7
Human MUC16 Predicted Functions
Predicted to act upstream of or within negative regulation of epithelial cell proliferation; negative regulation of interleukin-6 production; and negative regulation of wound healing. Is extrinsic component of membrane. Implicated in ovarian cancer. Biomarker of Sjogren’s syndrome; cholangiocarcinoma; dry eye syndrome; keratoconjunctivitis; and pancreatic cancer.
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Mouse Muc16 Target Information
- Target Symbol: Muc16, mucin 16
- Alias:
- 1110008I14Rik
- gene model 1480, (NCBI)
- Gm1480
- Gm21044
- LOC385009
- predicted gene, 21044
- RIKEN cDNA 1110008I14 gene
- NCBI_Gene: 73732
Mouse Muc16 Predicted Functions
Acts upstream of or within negative regulation of epithelial cell proliferation; negative regulation of interleukin-6 production; and negative regulation of wound healing. Located in external side of plasma membrane. Is expressed in several structures, including alimentary system; genitourinary system; mesothelium; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in ovarian cancer. Orthologous to human MUC16 (mucin 16, cell surface associated).
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Rat Muc16 Target Information
- Target Symbol: Muc16, mucin 16, cell surface associated
- Alias:
- LOC315451
- mucin 16
- mucin-16
- RGD1308422
- similar to ovarian cancer related tumor marker CA125
- NCBI_Gene: 315451
- 暂无
Rat Muc16 Predicted Functions
Predicted to act upstream of or within negative regulation of epithelial cell proliferation; negative regulation of interleukin-6 production; and negative regulation of wound healing. Located in extracellular space. Biomarker of ovarian carcinoma. Human ortholog(s) of this gene implicated in ovarian cancer. Orthologous to human MUC16 (mucin 16, cell surface associated).
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MUC16 Target News
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